Simulaciones de desplegamiento en folding@home

UNFOLDING OF THE DNA BINDING DOMAIN OF HIV INTEGRASE

HIV uses proteins to insert its genetic code into our DNA. The DNA
binding domain of HIV integrase (below) is the protein which HIV uses
to grab onto our DNA such that it can then connect its genetic code into
ours.

This movie shows a single trajectory of the unfolding of this protein
under extreme denaturating conditions.

UNFOLDING OF DESIGNED PROTEIN

This protein was designed by the Mayo Lab to fold into a "zinc finger"
fold (a protein fold which typically binds to DNA).