Revistas
2024
S H. Bidooki, J Quero, J Sánchez-Marco, T Herrero-Continente, I Marmol, R Lasheras, V Sebastian, M Arruebo, J Osada, MJ Rodriguez-Yoldi
Squalene In Nanoparticles Improves Antiproliferative Effect on Human Colon Carcinoma Cells Through Apoptosis by Disturbances in Redox Balance.
Int J Mol Sci 2024; 25:13048
S Espina-Cadena, D Casas-Deza, V Bernal-Monterde, Aroyo-Esteban, M P Garcia-Sobreviela, P Calmarza, A B Martínez-Martínez, J Osada, J M Arbones-Mainar
Unraveling the Association of Liver Steatosis and Fibrosis with Vitamin B12: A Cross-Sectional Study.
Metabolites 2024; 14:618
Bidooki, S. H.; Spitzer, L.; Petitpas, A.; Sánchez-Marco, J. Martínez-Beamonte, R.; Lasheras, R.; Pellerin, V.; Rodríguez-Yoldi, M.; Navarro, M. Á.; Osada, J.; Fernandes, S.
Chitosan Nanoparticles, a Novel Drug Delivery System to Transfer Squalene for Hepatocyte Stress Protection.
ACS Omega 2024, 9: 51379-51393
L.V. Herrera-Marcos, J.M. Arbones-Mainar and J. Osada
Lipoprotein Lipidomics as a Frontier in Non-Alcoholic Fatty Liver Disease Biomarker Discovery.
Int J Mol Sci 2024; 25:8285
J Quero, M. Paesa, C. Morales, G. Mendoza, J. Osada, J A. Teixeira, P. Ferreira-Santos, M. J Rodríguez-Yoldi.
Biological Properties of Boletus edulis Extract on Caco-2 Cells: Antioxidant, Anticancer, and Anti-Inflammatory Effects.
Antioxidants 2024; 13:908
S. H. Bidooki, C. Barranquero, J. Sánchez-Marco, R. Martínez-Beamonte, M. J. Rodríguez-Yoldi, M.A. Navarro, S.C.M. Fernandes and J. Osada
TXNDC5 Plays a Crucial Role in Regulating Endoplasmic Reticulum Activity through Different ER Stress Signaling Pathways in Hepatic Cells.
Int J Mol Sci 2024; 25:7128
R. Martínez-Beamonte, C. Barranquero, S. Gascón, J. Mariño, C. Arnal, G. Estopañán, M. J. Rodriguez-Yoldi, J. C. Surra, O. Martín-Belloso, I. Odriozola-Serrano, I. Orman, J. C. Segovia, J. Osada and M.A. Navarro.
Effect of virgin olive oil as spreadable preparation on atherosclerosis compared to dairy butter in Apoe-deficient mice.
J Physiol Biochem 2024; 80:671-683
Allaoui, Amine, Faiza Dehiba, Luis Vicente Herrera-Marcos, Maria-Jesus Rodríguez-Yoldi, Jesus Osada, and Ahmed Boualga
Postprandial Changes in Gene Expression of Hepatic Cholesterol Metabolism in Response to Two Protein Sources in the Rat.
Rom J Diabetes Nutr Metab Dis 2024; 31:143-49
S.H. Bidooki ,M.A. Navarro, S.C.M. Fernandes and J. Osada
Thioredoxin Domain Containing 5 (TXNDC5): Friend or Foe?
Curr. IssuesMol. Biol. 2024; 46:3134–3163.
L.V. Herrera-Marcos, Roberto Martínez-Beamonte, Carmen Arnal, Cristina Barranquero, J.J. Puente-Lanzarote, J.M. Lou-Bonafonte, G. Gonzalo-Romeo, G. Mocciaro, B. Jenkins, J.C. Surra, M.J. Rodríguez-Yoldi, V. Alastrué-Vera, J. Letosa, A. García-Gil, A. Güemes, A. Koulman and J. Osada
Lipidomic
signatures discriminate subtle hepatic changes in the progression of porcine
non-alcoholic steatohepatitis.
Am. J Physiol-Gastrointestinal and Liver Physiology 2024; 326:G411-G425
J. Sánchez-Marco, S.H. Bidooki, R. Abuobeid, C. Barranquero, T. Herrero-Continente, C. Arnal, R. Martínez-Beamonte, R. Lasheras J. C. Surra, M.A. Navarro, M.J. Rodríguez-Yoldi, M. Arruebo, V. Sebastian, J. Osada
Thioredoxin
domain containing 5 is involved in the hepatic storage of squalene into lipid
droplets in a sex-specific way.
J Nutr Biochem 2024; 124:109503
2023
S. H. Bidooki., Javier Sánchez-Marco, R. Martínez-Beamonte, T. Herrero-Continente, M.A. Navarro., M. J. Rodríguez-Yoldi and J. Osada
Endoplasmic
Reticulum Protein TXNDC5 Interacts with PRDX6 and HSPA9 To Regulate Glutathione
Metabolism and Lipid Peroxidation in the Hepatic AML12 Cell Line.
Int J Mol Sci 2023; 24:17131
R. Martínez-Beamonte, J. Sánchez-Marco, M. Gómez, G. Lázaro, M. Barco, T. Herrero-Continente, M. Serrano-Megías, D. Botaya, C. Arnal, C. Barranquero, J. C. Surra, J. Osada and M. A. Navarro
Dietary
proteins modulate high density lipoprotein characteristics in a sex-specific
way in Apoe-deficient mice.
Nutrition 2023; 116:112211
R. Abuobeid, L.V. Herrera-Marcos, C. Arnal, S.H. Bidooki, J. Sánchez-Marco, R. Lasheras, J.C. Surra, M.J. Rodríguez-Yoldi, R. Martínez-Beamonte and J. Osada
Differentially
Expressed Genes in Response to a Squalene-Supplemented Diet Are Accurate Discriminants
of Porcine Non-Alcoholic Steatohepatitis.
Int J Mol Sci 2023; 24:12552
I. Lazaro Lopez, J. Bobi, M. Cofan, G. Kapravelou, A. J. Amor, J. Surra, C. Gomez-Guerrero, E. Ortega, J. Osada, A. P. Dantas A. Sala-Vila
Walnut
inclusion in a palm oil-based atherogenic diet promotes traits predicting
stable atheroma plaque in Apoe-deficient mice.
Frontiers in Nutr 2023; 10:1079407
L.V. Herrera-Marcos, R. Martínez-Beamonte, Carmen Arnal, C. Barranquero, J.J. Puente-Lanzarote, T. Herrero-Continente, J. M. Lou-Bonafonte, G. Gonzalo-Romeo, G. Mocciaro, B. Jenkins, J.C. Surra, M. J. Rodríguez-Yoldi, J. C. Burillo, R. Lasheras, A. García-Gil, A. Güemes, A. Koulman and J. Osada
Dietary
squalene supplementation decreases triglyceride species and modifies phospholipid
lipidomic profile in the liver of a porcine model of non-alcoholic steatohepatitis.
J Nutr Biochem 2023; 112:109207
2022
M. Paesa, C. Ancín-Azpilicueta, G. Velderrain-Rodriguez, O. Martin-Belloso, O. Gualillo, J. Osada, M. J. Rodríguez-Yoldi, G. Mendoza.
Anti-Inflammatory
and Chondroprotective Effects Induced by Phenolic Compounds from Onion Waste
Extracts in ATDC-5 Chondrogenic Cell Line.
Antioxidants 2022; 11:2381
R.
Martínez-Beamonte, M. Ripalda, T. Herrero-Continente, C. Barranquero, A. Davalos,
M. C. López De Las Hazas, I. Alvarez, A.C. Sánchez-Gimeno, J. Raso, C. Arnal,
J.C. Surra, J. Osada and M.A. Navarro.
Pulsed
electric field increases the extraction yield of extra virgin olive oil without
loss of its biological properties.
Frontiers in Nutrition 2022;
9:1065543
J. Quero, J.C. Royo, B. Fodor, M. C. Gimeno, J. Osada, M. J.Rodríguez-Yoldi and E. Cerrada.
Sulfonamide-Derived
Dithiocarbamate Gold (I) Complexes Induce the Apoptosis of Colon Cancer Cells
by the Activation of Caspase 3 and Redox Imbalance
Biomedicines 2022; 10:1437
J. Quero, L.F. Ballesteros-Giraldo, P. Ferreira-Santos, G. Velderrain-Rodriguez, C.M.R. Rocha, R.N. Pereira, J. Teixeira, O. Martin-Belloso, J. Osada, M.J. Rodriguez-Yoldi.
Unveiling
The Antioxidant Therapeutic Functionality Of Sustainable Olive Pomace Active
Ingredients.
Antioxidants 2022; 11:828
R.
Abuobeid, J. Sánchez-Marco, M. J. Felices, C. Arnal, J. C. Burillo, R. Lasheras,
R. Busto, M. A. Lasunción, M. J. , Rodríguez-Yoldi, R. Martínez-Beamonte,
J. Osada
Squalene
through its post-squalene metabolites is a modulator of hepatic transcriptome
in rabbits.
Int J Mol Sci 2022; 23:4172
M. Paesa, D. Pires-Nogueira, G. Velderrain-Rodriguez, I., Esparza, N. Jiménez-Moreno, G. Mendoza, J. Osada, O. Martin-Belloso, M. , J. Rodriguez-Yoldi, C. Ancín-Azpilicueta.
Valorization
of Onion Waste by Obtaining Extracts Rich in Phenolic Compounds and Feasibility
of its Therapeutic Use on Colon Cancer.
Antioxidants 2022; 11:733
S. Hesamoddin-Bidooki, T. Alejo, J. Sánchez-Marco, R., Martínez-Beamonte, R. Abuobeid, J. C. Burillo, R. Lasheras, V., Sebastian, M. J. Rodríguez-Yoldi, M. Arruebo, J. Osada.
Squalene
Loaded Nanoparticles Effectively Protect Hepatic AML12 Cell Lines against
Oxidative and Endoplasmic Reticulum Stress in a TXNDC5-Dependent Way.
Antioxidants 2022; 11:581
J. Sánchez-Marco, R. Martínez-Beamonte, A. De Diego, T., Herrero-Continente, C., Barranquero, C. Arnal, J. Surra, M.A. Navarro, J., Osada
Thioredoxin
Domain Containing 5 Suppression Elicits Serum Amyloid A-Containing High-Density
Lipoproteins.
Biomedicines 2022; 10:709
L.V.
Herrera-Marcos, R. Martínez-Beamonte, M. Macías-Herranz, C. Arnal, C. Barranquero,
J.J. Puente-Lanzarote, S. Gascón, T. Herrero-Continente, G. Gonzalo-Romeo,
V. Alastrué-Vera, D. Gutiérrez-Blázquez, J. M. Lou-Bonafonte, J.C. Surra,
M. J. Rodríguez-Yoldi, A García-Gil, A. Güemes and J Osada
Hepatic
Galectin-3 is associated with lipid droplet area in non-alcoholic steatohepatitis
in a new swine model.
Scientific Reports 2022; 12:1024
2021
J. Quero, J. Osada, F. Ruigh, M. C. Gimeno, E. Cerrada and M.J. Rodríguez-Yoldi
Gold(I) Complexes Bearing Alkylated 1,3,5-Triaza-7-phosphaadamantane Ligands as
Thermoresponsive Anticancer Agents in Human Colon Cells.
Biomedicines 2021; 9:1848
Beamonte,
R. Sánchez-Marco, J. Felices, M.J. Barranquero, C. Gascón, S. Arnal, C. Burillo,
J. C. Lasheras, R. Busto, R. Lasunción, M. A. Rodríguez-Yoldi M. J. and Osada
J.
Dietary
squalene modifies plasma lipoproteins and hepatic cholesterol metabolism in
rabbits
Food and Function 2021; 12:
8141-8153
Velderrain-Rodríguez, G. R. Quero, J. Osada, J. Martín-Belloso, O. and Rodríguez-Yoldi, M.J.
Phenolic-rich
extracts from avocado fruit residues as functional food ingredients with antioxidant
and antiproliferative properties.
Biomolecules 2021; 11:977
I. Mármol, J. Quero, R. Ibarz, P. Ferreira-Santos, J. A. Teixeira, Cristina M.R. Rocha, M. Pérez-Fernández, S. García-Juiz, J. Osada, O. Martín-Belloso and M. J. Rodríguez-Yoldi
Valorization
of agro-food by-products and their potential therapeutic applications
Food and Bioproducts Processing, 2021; 128:247–258
R. Martínez-Beamonte, J. Sánchez-Marco, G. Lázaro, M. Barco, T. Herrero-Continente, M. Serrano-Megías, D. Botaya, C. Arnal, C. Barranquero, J.C. Surra, J. Osada and M.A. Navarro
Dietary
avian proteins are comparable to soybean proteins on the atherosclerosis development
and fatty liver disease in Apoe-deficient mice
Nutrients 2021; 13:1838
J Quero, N Jiménez-Moreno, I Esparza, J Osada, E. Cerrada, C. Ancín-Azpilicueta, M. J. Rodríguez-Yoldi
Grape
stem extracts with potential anticancer and antioxidant properties.
Antioxidants 2021; 10:243
2020
R.
Abuobeid, L. Herrera-Marcos, M. A. Navarro, C. Arnal, R. Martínez-Beamonte,
J.C. Surra and J. Osada.
Dietary
erythrodiol modifies hepatic transcriptome in a sex and dose-dependent way.
INT. J. MOL. SCI 2020; 21:7331
C. Gabás-Rivera, E. Jurado-Ruiz, A. Sánchez-Ortiz, E. Romanos, R. Martínez-Beamonte, M. A. Navarro, J.C. Surra, C. Arnal, M.J., Rodríguez-Yoldi, C. Andrés-Lacueva and J. Osada.
Dietary
squalene induces Cytochromes Cyp2b10 and Cyp2c55 independently of sex, dose
and diet in several mouse models.
MOLECULAR NUTRITION & FOOD
RESEARCH 2020; 64:2000354
R. Garriga, T. Herrero-Continente, M. Palos, V.L. Cebolla, J. Osada, E. Muñoz and M.J. Rodríguez-Yoldi.
Toxicity
of carbon nanomaterials and their potential application as drug delivery systems:
in vitro studies in Caco-2 and MCF-7 cell lines.
NANOMATERIALS 2020; 10:1617
S Sancho-Knapik;
O Pastor; C Barranquero; L V Herrera-Marcos; N Guillén; C Arnal; S Gascón; M A Navarro; M J Rodríguez-Yoldi; R Busto; M A Lasunción
and J Osada.
Hepatic
Synaptotagmin 1 is involved in the remodelling of liver plasma- membrane lipid
composition and gene expression in male ApoE-deficient mice consuming a Western
diet.
BBA - Molecular and Cell
Biology of Lipids 2020; 1865:158790
J. Lozano-Gerona, A. Oliván-Viguera, P. Delgado-Wicke, V. Singh, B. M. Brown., E. Tapia-Casellas, E. Pueyo, M.S. Valero, A.L. Garcia-Otín, P. Giraldo, E. Abarca-Lachen, J.C. Surra, J. Osada, K.L Hamilton, S. P. Raychaudhuri, M. Marigil, Á. Juarranz, H. Wulff, H.Miura, Y. Gilaberte and R. Koller
Conditional
KCa3.1-transgene induction in murine skin produces pruritic eczematous dermatitis with severe epidermal hyperplasia and hyperkeratosis.
PLoS One 2020; 15(3):e0222619.
L. Cañes, I. Marti-Pamies, C. Ballester-Servera, A. Herraiz-Martinez, J. Alonso, M. Galán, J Nistal, P. Muniesa, J. Osada, L. Hove-Madsen, C. Rodriguez and J. Martínez-González
Neuron-derived
orphan receptor-1 modulates cardiac gene expression and exacerbates angiotensin
II-induced cardiac hypertrophy.
CLINICAL SCIENCE 2020; 134:359-377
B Martínez-Soriano, A. Güemes, G. Pola, A. Gonzalo, P. Palacios-Gasos, A. C. Navarro, R. Martínez-Beamonte, J. Osada and J. J. García
Effect of melatonin as an antioxidant drug to reverse hepatic steatosis. Experimental model.
CAN J GASTROENTEROL HEPATOL
2020: 7315253
I Mármol, N Jiménez-Moreno, C Ancín-Azpilicueta, J Osada, E Cerrada and M. J. Rodríguez-Yoldi.
A
combination of rosa canina extracts and gold complex favors apoptosis of caco-2
cells by increasing oxidative stress and mitochondrial dysfunction.
ANTIOXIDANTS 2020; 9:17
L.V.
Herrera-Marcos, S. Sancho-Knapik, C. Gabás-Rivera, C. Barranquero, S. Gascón,
E. Romanos, R. Martínez-Beamonte, M. A. Navarro, J.C. Surra, C. Arnal, J.
A. García-De-Jalón, M. J. Rodríguez-Yoldi, M. Tena-Sempere, C. Sánchez-Ramos,
M. Monsalve and J. Osada.
Pgc1a
is responsible for the sex differences in hepatic Cidec/Fsp27ß
mRNA expression in hepatic steatosis of mice fed a western diet.
AM J PHYSIOL ENDOCRINOL AND
METABOLISM 2020; 318:249-261
Martinez-Beamonte, R., T. Sanclemente, J. C. Surra, Osada, J.
Could
squalene be an added value to use olive by-products?
J SCIENCE FOOD AGRICULTURE
2020; 100:915-925
2019
J
J Gaforio , F Visioli, C Alarcón-de-la-Lastra, O Castañer,M Delgado-Rodríguez,
M Fitó, A F Hernández, J R Huertas, M A Martínez-González, J A Menendez ,
J de la Osada, A Papadaki, T Parrón, J E Pereira, M A Rosillo, C Sánchez-Quesada,
L Schwingshackl, E Toledo and A M Tsatsakis.
Virgin
Olive Oil and Health: Summary of the III International Conference on Virgin
Olive Oil and Health Consensus Report, Jaén (Spain)2018.
NUTRIENTS 2019, 11: 2039
M-C López De Las Hazas, R Martin-Hernández, M C Crespo, J Tomé-Carneiro, L Del Pozo-Acebo, Mb. Ruiz-Roso, J C. Escola-Gil, J Osada, M P. Portillo, J A Martinez,
M A. Navarro, L Rubió, M J Motilva, F Visioli and A Dávalos.
Identification
and validation of common molecular targets of hydroxytyrosol.
FOOD & FUNCTION 2019, 10:4897-4910.
M. J. Felices, S. Escusol, R. Martinez-Beamonte, S. Gascón, C. Barranquero, C. Sanchez-De-Diego, J. Osada, M. J. Rodríguez-Yoldi.
LPS-squalene
interaction on D-galactose intestinal absorption.
JOURNAL OF PHYSIOLOGY AND
BIOCHEMISTRY 2019, 75:329-340
Allaoui
A, Gascón S, Benomar S, Quero J, Osada J,Nasri M, Rodriguez-Yoldi Mj,
Boualga A.
Protein
hydrolysates from fenugreek (Trigonella foenum graecum) as nutraceutical
molecules in colon cancer.
NUTRIENTS 2019, 11: 724
2018
Allaoui
A, Barranquero C, Yahia S, Herrera-Marcos LV, Benomar S, Jridi M, Navarro
MA, Rodriguez-Yoldi Mj, Nasri M, Osada J, Boualga A.
Fenugreek
proteins and their hydrolysates prevent hypercholesterolemia and enhance the
HDL antioxidant properties in rats.
NUTRITION & FOOD SCIENCE
48, 973-989, 2018.
Lou-Bonafonte Jm, Martinez-Beamonte, R., T. Sanclemente, J. C. Surra,
Lv Herrera-Marcos, Sanchez-Marco J, Arnal C, Osada, J.
Current
insights into the biological action of squalene.
MOL NUTR FOOD RES. 62:1800136,
2018.
Martinez-Beamonte, R., O. Alda, T. Sanclemente, M. J. Felices, S. Escusol,
C. Arnal, L.V. Herrera-Marcos, S. Gascón, J. C. Surra, Osada, J., M. J. Rodríguez-Yoldi.
Hepatic
subcellular distribution of squalene changes according to the experimental
setting.
JOURNAL OF PHYSIOLOGY AND
BIOCHEMISTRY 74:531-538, 2018.
Mendiara,
I.; Domeno, C.; Nerin, C.; Geurts, A. M.; Osada, J.; Martinez-Beamonte, R.
Determination
of total plasma oxysterols by enzymatic hydrolysis, solid phase extraction
and liquid chromatography coupled to mass-spectrometry
J. PHARM. BIOMED. ANAL. 150:
396-405, 2018
Herrera-Marcos,
L.V.; Lou-Bonafonte, J.M.; Martinez-Gracia M.V.; Arnal, C.; Navarro, M.A.;
Osada, J.
Prenylcysteine
oxidase 1, a pro-oxidant enzyme of low density lipoproteins
FRONTIERS IN BIOSCIENCE,
Landmark, 23, 1020-1037, January 1, 2018
2017
Herrera-Marcos,
L.V.; Lou-Bonafonte, J.M.; Arnal, C.; Navarro, M.A.; Osada, J.
Transcriptomics
and the mediterranean diet: a systematic review.
NUTRIENTS 9: 472, 2017
S. Yahia, S. Benomar, F. Dehiba, A. Allaoui, N. Guillen, M.J. Rodriguez-Yoldi, J. Osada; A. Boualga.
Hypocholesterolemic
and antioxidant efficiency of chickpea (Cicer arietinum) protein
hydrolysates depend on its degree of hydrolysis in cholesterol-fed rat.
NUTRITION & FOOD SCIENCE.
47: 254-269, 2017
J. M. Lou-Bonafonte, C. Gabás-Rivera,
M.A. Navarro; J. Osada.
The
search for dietary supplements to elevate or activate circulating paraoxonases.
INT J MOL SCI. 18: 416, 2017.
C. Sanz-García, A. Sánchez,
C. Contreras-Jurado, C. Cales, C. Barranquero, M. Muñoz, R. Merino, P. Escudero,
M.J. Sanz, J. Osada, A. Aranda, S. Alemany.
Map3K8
modulates monocyte state and atherogenesis in apoE-/- mice.
ARTERIOSCLER THROMB VASC
BIOL, 37(2):237-246, 2017.
2016
Sevelsted Møller,
L. Fialla, Ad. Schierwagen R. Biagini M. Liedtke C. Laleman W. Klein S. Reul W. Koch Hansen L. Rabjerg M. Singh
V. Surra J. Osada J. Reinehr R. De Muckadell Ob. Köhler R. Trebicka J.
The
calcium-activated potassium channel KCA3.1 is an important modulator of hepatic
injury.
SCI REP. 6: 28770, 2016.
S. Sancho-Knapik, C. Gabas-Rivera,
S. Gascon, E. Romanos, R. Martinez-Beamonte, M.A. Navarro, J.C. Surra, C.
Arnal and J. Osada.
Diet
and sex hormones regulate hepatic synaptotagmin 1 mRNA in mice.
FRONTIERS IN BIOSCIENCES
8: 129-142, 2016.
2015
J. M. Lou-Bonafonte, C. Gabás-Rivera,
M.A. Navarro and J. Osada.
PON1
and mediterranean diet.
NUTRIENTS 7: 4068-4092, 2015.
S. Sancho-Knapik, N. Guillén
and J. Osada.
Cloning
and expression of hepatic synaptotagmin 1 in mouse.
GENE. 562: 236–243,
2015
S. Benomar, A. Boualga, S.
Yahia, F. Dehiba, N. Guillén, Mj. Rodriguez-Yoldi and J. Osada.
Differential
antioxidative and hypocholesterolemic responses to two fish protein hydrolysates
(Sardina pilchardus and Boops boops) in cholesterol-fed rats.
NUTRITION AND FOOD SCIENCE
45: 448-466, 2015
M.J.
Rodríguez-Yoldi, S. Gascón, C. Barranquero, A. Garcia_Barrios
and J. Osada
Involvement
of intracellular signalling in the IL-1ß inhibitory effect on fructose
intestinal absorption.
J CELL PHYSIOL. 230: 896-902; 2015
2014
E.
Horna-Terrón, A. Pradilla-Dieste, C. Sánchez-De-Diego and J.
Osada.
TXNDC5,
a newly discovered disulfide isomerase with a key role in cell physiology
and pathology.
INT J MOL SC. 15: 15, 23501-23518;
2014.
A.
Bassols, C. Costa, P. D. Eckersall, J. Osada, J. Sabrià and J. Tibau.
The
pig as an animal model for human pathologies: a proteomics perspective.
PROTEOMICS CLINICAL APPLICATIONS. 8:715-31, 2014
C. Gabás-Rivera, C.
Barranquero, R. Martínez-Beamonte, M.A. Navarro, J.C. Surra and J.
Osada.
Dietary squalene
increases high density lipoprotein-cholesterol and paraoxonase 1 and decreases
oxidative stress in mice.
PLOS ONE, 9:e104224, 2014
Orriols M, Guadall A, Galán
M, Martí-Pàmies I, Varona S, Rodríguez-Calvo R, Briones
AM, Navarro MA, De Diego A, Osada J, Martínez-González J and
Rodríguez C.
Lysyl
oxidase (LOX) in vascular remodelling. Insight from a new animal model.
THROMB HAEMOST. 112:812-24. 2014
S. Olivan, R. Martínez-Beamonte,
A.C. Calvo, J.C. Surra, R. Manzano, C. Arnal, Osta, R. and J. Osada.
Extra
virgin olive oil intake delays the development of amyotrophic lateral sclerosis
associated with reduced reticulum stress and autophagy in muscle of sod1g93a
mice.
J NUTR BIOCHEM. 25:885-92. 2014
Lezcano Ej, Iñigo P,
Larraga Am, Barranquero C, Gimenez I, and Osada J.
Caloric
restriction or telmisartan control dyslipidemia and nephropathy in obese diabetic
Zücker rats.
DIABETOL METAB SYNDR. 2014 Jan 27;6(1)
2013
Osada,
J.
The
use of transcriptomics to unveil the role of nutrients in mammalian liver.
ISRN NUTRITION. 2013. Article ID 403792.
C.
Gabás-Rivera, R. Martínez-Beamonte, J.L. Ríos, M.A. Navarro,
J.C. Surra, C. Arnal, M.J. Rodríguez-Yoldi and J. Osada
Dietary
oleanolic acid mediates circadian clock gene expression in liver independently
of diet and animal model but requires apolipoprotein A1.
J NUTR BIOCHEM. 2013; 24:
2100-9
C.
Viñuales, S. Gascón, C. Barranquero, J. Osada and Mª J.
Rodríguez-Yoldi
Interleukin-1beta
reduces galactose transport in intestinal epithelial cells in a NF-kB and
protein kinase C-dependent manner.
VET IMMUNOL AND IMMUNOPATHOL.
2013; 155:171-81
Julve
J, Escolà-Gil Jc, Rodríguez-Millán E, Martin-Campos Jm,
Jauhiannen M, Quesada H, Renteria-Obregón Im, Osada J, Sanchez-Quesada
Jl, Blanco-Vaca F.
Methionine-induced
hyperhomocysteinemia impairs the antioxidant ability of high-density lipoproteins
without reducing in vivo macrophage-specific reverse cholesterol transport.
MOL NUTR FOOD RES. 2013; 57:1814–1824
Rodríguez-Calvo
R, Guadall A, Calvayrac O, Navarro M. A., Alonso J, Beatriz Ferrán,
De Diego A, Muniesa P, J Osada, C Rodríguez, Martínez-González,
J.
Over-expression
of neuron-derived orphan receptor-1 (NOR-1) exacerbates neointimal hyperplasia
after vascular injury.
HUMAN MOL GENETICS 2013; 22:1949-59.
Martínez-Beamonte
R, Lou-Bonafonte, J.M., Martínez-Gracia, M.V., and Osada J.
Sphingomyelin
in high-density lipoproteins: structural role and biological function.
INT J MOL SCI. 2013; 14: 7716-7741
Martínez-Beamonte
R, Navarro Ma, Acin S, Guillén N, Barranquero C, Arnal C, Surra J,
Osada J.
Postprandial
changes in high density lipoproteins in rats subjected to gavage administration
of virgin olive oil.
PLOS ONE. 2013. 10.1371/journal.pone.0055231
J
C. Surra, C. Barranquero, M. P. Torcal, I.Orman, J. C. Segovia,.N. Guillén,
M. A. Navarro, C. Arnal and Osada J.
In
comparison with palm oil, dietary nut supplementation delays progression of
atherosclerotic lesions in female apoE-deficient mice.
BR. J NUTR. 2013; 109: 203-209
2012
Gonzalo
Ma, Martínez-Beamonte R, Palacios P, Marín J, Castiella T, Surra
J, Burdío F, Sousa R, Güemes A, Osada J, García-Gil A.
Analysis
of tissue bioimpedance as a measurement of liver steatosis: experimental model
in large animals.
TRANSPLANT PROC. 2012; 44:1579-83
A.
Ramírez-Torres, S. Barceló-Batllori, R. Martínez-Beamonte,
M. A. Navarro, J. C. Surra, C. Arnal, N. Guillén, S. Acín and
Osada J.
Proteomics
and gene expression analyses of squalene-supplemented mice identify microsomal
thioredoxin domain-containing protein 5 changes associated with hepatic steatosis.
J PROTEOMICS. 77: 27 – 39. 2012.
C.
Viñuales, S. Gascón, C. Barranquero, J. Osada and Mª J.
Rodríguez-Yoldi.
Inhibitory
effect of IL-1ß on galactose intestinal absorption in rabbits.
CELL PHYSIOL AND BIOCHEM. 30:173-186. 2012
M.
Nuño-Ayala, N. Guillen, C. Arnal, J.M. Lou-Bonafonte, A. De Martino,
J.-A. García-De-Jalón, S. Gascón, L. Osaba, J.Osada and
M. A. Navarro.
Cystathionine
ß-synthase deficiency causes infertility by impairing decidualization
and gene expression networks in uterus implantation sites.
PHYSIOL GENOMICS. 44:702-16. 2012
L.
Fraile, E. Crisci, L. Córdoba, M. A. Navarro, J. Osada and M. Montoya.
Immunomodulatory
properties of phytosterols in pigs.
INTERNATIONAL IMMUNOPHARMACOLOGY. 13:316-321. 2012
J.M.
Lou-Bonafonte, M. A. Navarro, C. Arnal, and Osada J.
Efficacy
of bioactive compounds from extra virgin olive oil to modulate atherosclerosis
development.
MOL NUTR FOOD RES. 56:1043-57. 2012
Lou-Bonafonte,
J.M., Fitó M, Covas Mi, Farràs M, and Osada J.
HDL-related
mechanisms of olive oil protection in cardiovascular disease.
CURRENT VASC PHARMACOL.10: 392-409. 2012
A.
Ramírez-Torres, S. Barceló-Batllori, E. Fernández-Vizarra,
M. A. Navarro, C. Arnal, N. Guillén, S. Acín and Osada J.
Proteomics
and gene expression analyses of mitochondria from squalene-treated apoE-deficient
mice identify short-chain specific acyl-CoA dehydrogenase changes associated
with fatty liver amelioration.
J PROTEOMICS 75:2563-2575. 2012
2011
Lou-Bonafonte,
J.M., Arnal, C. and Osada J.
New
genes involved in hepatic steatosis.
CURRENT OPINION IN LIPIDOLOGY 22:159-64. 2011.
Martinez-Beamonte,
R., Navarro, M. A., Larraga, A., Strunk, M., Barranquero, C., Acin, S., Guzmán,
M.A., Iñigo P. and Osada J.
Selection
of reference genes for gene expression studies in rats.
J BIOTECHNOL 151:325-34. 2011. http:// 10.1016/j.jbiotec.2010.12.017
Martinez-Beamonte,
R., Navarro, M. A., Guillén, N., Acin, S., Arnal, C., Guzmán,
M.A. and Osada J.
Postprandial
transcriptome associated with virgin olive oil intake in rat liver.
FRONTIERS IN BIOSCIENCES 3:11-21. 2011
2010
García-Barrios, A, Guillén,
N, Gascón, S, Osada, J, Vázquez, CM, Miguel-Carrasco, JL and
Rodríguez-Yoldi MJ.
Nitric
oxide involved in the IL-1beta-induced inhibition of fructose intestinal transport.
J CELL BIOCHEM. 111:1321–1329. 2010
Nuño, M., Guillén,
N., Navarro, M. A., Lou-Bonafonte, J.M., Arnal, C., Gascón, S., Barranquero,
C., Godino, J., Royo, M., Sarría, A.J., Guzmán, M.A., Hernandez,
E., Bregante, M. A., García-Gimeno, M. A. and Osada J.
Cysteinemia,
rather than homocysteinemia, is associated with plasma apolipoprotein A-I
levels in hyperhomocysteinemia.
ATHEROSCLEROSIS 212:268-273, 2010
Surra, J.C., Guillén,
N., Arbonés-Mainar, J. M., Barranquero, C., Navarro, M. A., Arnal,
C., Orman, I., Segovia, J.C. and Osada, J.
Sex as a profound
modifier of atherosclerotic lesion development in apolipoprotein E-deficient
mice with different genetic backgrounds.
J ATHEROSCLER AND THROMB 17: 712-721, 2010
López-Miranda J, Pérez-Jiménez
F, Ros E, De Caterina R, Badimón L, Covas MI, Escrich E, Ordovás
JM, Soriguer F, Abiá R, Alarcón de la Lastra C, Battino M, Corella
D, Chamorro-Quirós J, Delgado-Lista J, Giugliano D, Esposito K, Estruch
R, Fernandez-Real JM, Gaforio JJ, La Vecchia C, Lairon D, López-Segura
F, Mata P, Menéndez JA, Muriana FJ, Osada J, Panagiotakos DB, Paniagua
JA, Pérez-Martinez P, Peinado MA, Pineda-Priego M, Poulsen HE, Quiles
JL, Ramírez-Tortosa MC, Ruano J, Serra-Majem L, Solá R, Solanas
M, Solfrizzi V, R de la Torre-Fornell, Trichopoulou A, Uceda M, Villalba-Montoro
JM, Villar-Ortiz JR, Visioli F, Yiannakouris N.
Olive
oil and health: summary of the ii international conference on olive oil and
health consensus report, Jaén and Córdoba (Spain)
2008.
NUTR METAB CARDIOVASC DIS. 20:284-94, 2010
Surra, J.C., Guillén,
N., Barranquero, C., Arbonés-Mainar, J. M., Navarro, M. A., Gascón,
S., Arnal, C. Godino, J., Guzmán, M. A., Díaz-Gil, J.J. and
Osada J.
Sex-dependent
effect of liver growth factor on atherosclerotic lesions and fatty liver disease
in apolipoprotein E knockout mice.
HISTOL AND HISTOPATHOL 25:609-18, 2010
Alemany, R., Navarro, M. A.,
Vögler, O., Perona, J. S., Osada J. and Ruiz-Gutiérrez, V.
Olive
oils modulate fatty acid content and signaling protein expression in apolipoprotein
E knockout mice brain.
LIPIDS 45:53-61, 2010
Navarro,M.
A., Badimon,L., Rodriguez, C., Arnal,C., Noone,E., Roche,H., Osada J. and
Martínez-González, J.
Trans-10,cis-12-CLA
dysregulate lipid and glucose metabolism and induce hepatic NR4A receptors.
FRONTIERS IN BIOSCIENCE 2: 87-97, 2010
2009
Guillén,
N., Navarro, M. A., Arnal, C. Noone, E., Arbonés-Mainar, J. M., Acín,
S., Surra, J.C., Muniesa, P., Roche, H. and Osada J.
Microarray
analysis of hepatic gene expression identifies new genes involved in steatotic
liver.
PHYSIOL GENOMICS 37: 187-198, 2009
Carnicer,
R. Guillén, N., Arbonés-Mainar, J. M., Navarro, M. A. Guzmán,
M.A. Barranquero, C., Arnal, C. Gascón, Acín,S., Mourelle, M.
and Osada J.
Nitric
oxide-releasing agent, La419, reduces atherogenesis in apolipoprotein E deficient
mice.
NAUNYN-SCHMIEDEBERG ARCHIVES OF PHARMACOLOGY 379:489 – 500. 2009
Guillen,
N., Acín, S., Navarro, M.A., Martínez-Gracia, M.V., Surra, J.C.,
Arnal, C., Lou-Bonafonte, J.M., Muniesa, P. and Osada, J.
The
knowledge of biological action of extra virgin olive oil by using the mouse
lacking apolipoprotein E.
REV ESP CARDIOL. 62: 294-304. 2009 
Guillen,
N. Acín, S. Surra, J.C. Arnal, C. Godino, J. García-Granados,
A. Muniesa, P. Ruiz-Gutiérrez, V. and Osada, J. Apolipoprotein
e determines the hepatic transcriptional profile of dietary maslinic acid
in mice.
J. NUTR. BIOCHEM. 20: 882-893, 2009
2008
Amador,
P., Marca, M. C., García-Herrera, J., Lostao, M.P., Guillén,
N., Osada J. and Rodríguez-Yoldi, M. J.
Lipopolysaccharide
induces inhibition of galactose intestinal transport in rabbits in vitro.
CELL PHYSIOL BIOCHEM 22: 715-72, 2008
Carnicer,
R., Guzman; M.A., Acín S. Surra, J. C., Navarro, M. A. Arnal, C. Arbonés-Mainar,
J. M., Morales, R y Osada J.
Genetic background in
apolipoprotein A-I and cystathionine ß-synthase deficiency.
FRONTIERS IN BIOSCIENCE 13: 5155-5162, 2008
Carnicer, R. Navarro, M. A. Guillén, N. Arbonés-Mainar, J. M.
Surra, J. C Acín S. y Osada J.
Simvastatin
reverses the hypertension of heterozygous mice lacking cystathionine ß-synthase
and apolipoprotein A-I.
NAUNYN-SCHMIEDEBERG ARCHIVES OF PHARMACOLOGY 377: 35-43, 2008
N.
Guillén, S. Acín, M. A. Navarro, J. S. Perona, J. M. Arbonés-Mainar,
C. Arnal, A.J. Sarría, J. C. Surra, R. Carnicer, I. Orman, J. C. Segovia,
V. Ruiz-Gutiérrez y J. Osada.
Squalene
in a sex-dependent manner modulates atherosclerotic lesion which correlates
with hepatic fat content in apoE- knockout male mice.
ATHEROSCLEROSIS 197: 72-83, 2008
García-Herrera,
J.; Marca, M.C.; Brot-Laroche, E.; Guillen, N.; Acín, S.; Navarro,
M. A.; Osada, J.; Rodríguez-Yoldi, M.J.
Proteinkinases, TNF-alpha
and proteasome contribute in the inhibition of fructose intestinal transport
by sepsis "in vivo”.
AMERICAN
JOURNAL PHYSIOLOGY: GI AND LIVER PHYSIOLOGY 294: G155-164, 2008
